NMN Powder From Wholesale Ingredients manufacturer in China

Shenzhen Hygieia Biotechnology Co., Ltd.  focuses on the R & D, production and sales of new dietary supplement raw materials. In 2019, we realized the industrialization of high-purity Nicotinamide Mononucleotide (NMN) based on a new enzymatic process, with a number of independent intellectual property rights. In the future, Hygieia will introduce computer AI-design technology into protein artificial assembly, and combine with new enzyme engineering technology to achieve more technological breakthroughs.  In addition, we actively participate in the research projects with domestic and foreign research institutions, help promote the progress of NMN in clinical research, continuously expand the research of NMN application and explore related indications, and provide more basic research data support for NMN industry chain! We focus on anti-aging, focus on health, and share the future with you! What is NMN? NMN, the abbreviation of Nicotinamide mononucleotide, is a nucleotide derived from ribose and nicotinamide. Like NR, NMN is a derivative of niacin, and humans have enzymes that can use NMN to increase NAD levels. NMN is a natural molecule that occurs in all life forms. It is already present in your body and permanently used and consumed by all your cells. This super nutrient has been found to be essential to your cells’ health, from metabolism to repair, radically changing our approach to energy and longevity. Hygieia Biotech

NMN: NAD+ exists in all living organisms and is well known as a coenzyme in oxidation−reduction reaction. Recent research has drawn attention to its relation to “sirtuin” represented by NAD+−dependent protein deacetylases such as Sirt1 and Sirt3. Because Sirt1 is reported to regulate various life phenomena as aging, people is especially paying high attention to “Anti-aging effect” associated with the activated sirtuin through Sirtuin/SIRT1−activating components (STACs) as represented by resveratrol. Meanwhile, sirtuin is NAD+−dependent and increase of cellular NAD+ level is expected to have similar effects to the STACs, thus nicotinamide mononucleotide, an intermediate of NAD+ biosynthesis, is also in the spotlight. While absorption of nicotinamide mononucleotide into body and its functional mechanism remain unclear in many respects and are being studied, it is reported that administration tests of nicotinamide mononucleotide into mice show improvement of high fat diet-induced glucose intolerance1), restoration of mitochondrial dysfunction with age2) and reduction of infarct area in response to ischemia/reperfusion3), and that the other chronic administration study in mice indicates rescue effect of age-associated decline in neural stem cells4). Application of nicotinamide mononucleotide for prevention and diagnosis of age-dependent diseases such as diabetes, neurodegenerative disorder, cardiac disease etc. raises high expectation for anti-aging.

NMN manufacturer: (a)Whitening and UV protection effects_ NMN has been recognized as a cosmetic ingredient for its firmness and luster, and it is thought that supplementing NMN can improve the condition of the skin. Effepharm is applying for a patent while conducting UV tests on the skin with NMN. (b)Improvement of cognitive function and memory_ Alzheimer’s disease is caused by the deposition of amyloid β peptide (Aβ). NMN reduced the accumulation of ROS in hippocampal sections of amyloid β peptide by restoring NAD + and ATP. Studies have shown that cognitive function in AD model mice has been restored. (c)Promotion of blood circulation and improvement of heart function_Research studies have shown that NMN has the potential to prevent local ischemia. IPC stimulates SIRT1 and Sirt1 supports the delivery of blood throughout the body as a NAD + -dependent protein deacetylase. By activating Sirt1, NMN protects the heart and prevents ischemia and reperfusion. (d)Brain activation and prevention of neurological disorders_ Having healthy and active mitochondria makes you less susceptible to neurodegenerative diseases. NMN is likely to help prevent neurodegenerative diseases by increasing NAD + levels and increasing mitochondrial activity levels. (e)Obesity control and fat burning effect_ NMN works on the metabolism of adipose tissue and has the effect of burning the fat accumulated in the body. In a study, NMN intake improved insulin secretion, increased adiponectin, and showed a significant decrease in free fatty acids (FFA). (f)Suppression of aging and activation of cells_ NAD + levels decrease with age. Studies have shown that NMN is enzymatically converted to NAD. When NMN activates the sirtuin gene, NAD + increases, which can be expected to improve physical function and suppress aging. NMN manufacturer

anti-aging ingredients: Is there any skin-care term that’s bigger—and more loaded—than antiaging? In a society that puts such a premium on a youthful appearance, the claims surrounding antiaging ingredients in skin-care products are…challenging, to say the least. The truth is that, really, nothing you do with skin-care can completely prevent, halt, or reverse the very normal and natural aging process that we all experience. And the rate at which your skin shows age depends on many different factors, including your genetics and your environment as well as your skin-care habits. And, of course, you shouldn’t feel like you have to address any of the skin changes we associate with aging, like wrinkles, fine lines, or dark spots. Having wrinkles is not a sign of a health issue, and whether or not you want to try to reduce their appearance is entirely up to you. So what do we do with these so-called antiaging skin-care products? Well, many of the most potent “antiaging” ingredients in these serums and creams do have well-established benefits, some of which may translate to a youthful complexion for some people. If you want to manage fine lines and wrinkles, for instance, you might want something that hydrates and moisturizes, which can make the skin look more plump. And products that gently exfoliate the skin will help reduce several different signs of aging, including texture and pigmentation issues, as well as manage acne. This is also one area of skin care that’s constantly seeing new innovations that may or may not have actual evidence behind them. So, here are the antiaging ingredients that have stood the test of time—the ones dermatologists recommend to SELF editors over and over again. If you’re looking for something to help manage signs of aging, these are the ingredients you should look out for in skin-care products.

Sunscreen_ It’s probably no surprise that sunscreen is number one on this list, and if you’re only going to do one thing for your skin, sunscreen should be it! By using sunscreen that has broad spectrum protection—meaning it protects against both UVA and UVB rays—and at least SPF 30, you can help prevent sun damage.That damage can cause both serious issues, like skin cancer, and more cosmetic issues, like breaking down the collagen and elastin that keeps your skin firm and plump. Over time, that collagen breakdown can lead to premature signs of aging, like sagging skin and wrinkles. Sun exposure can also cause dark age spots and can darken other forms of hyperpigmentation, like melasma.

Vitamin C_ One of the most common active ingredients in skin-care products today, vitamin C acts as an antioxidant to counteract and protect against free radical damage, Shari Lipner, M.D., Ph.D., dermatologist at Weill Cornell Medicine and New York-Presbyterian, told SELF previously. Plus, it can also be used to effectively brighten dark spots over time.But it can also be a surprisingly tricky ingredient to use correctly. It’s sensitive to light, for instance, so it’s important to only buy vitamin C products that are in airless, opaque packaging that protect it from degrading. And it also comes in varying concentrations (between 5% and 20%), which means the effects—and side effects, like irritation—may vary greatly between products.

Niacinamide_This increasingly popular skin-care ingredient is a form of vitamin B3 that has shown promise in fighting free radical damage, brightening dark spots, and managing acne. And those with sensitive skin will be pleased to know that some research shows it can brighten skin with fewer side effects or irritation than other first-line treatments, like hydroquinone. Although your dermatologist can’t prescribe a niacinamide product on its own, this ingredient can be compounded into many other topical prescriptions, Laura Ferris, M.D., Ph.D., associate professor in the department of dermatology at the University of Pittsburgh, told SELF previously.

Glycolic acid_One of two major alpha-hydroxy-acids (AHAs), glycolic acid a chemical exfoliant that’s regularly used in products like peels and exfoliating toners, pads, cleansers, and creams. It works by dissolving the bonds between skin cells, SELF explained previously. That way, when you wipe off your skin, you take away those skin cells and reveal the smoother skin underneath.Glycolic acid is especially helpful for reducing signs of aging, like hyperpigmentation, fine lines, and wrinkles. But know that its effects vary depending on the concentration of glycolic acid in the product you’re using. Milder over-the-counter products—like toners, for instance—generally contain around 5% to 7% glycolic acid and max out around 10%. These can be used a few times a week.

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